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B12 shots for cats are a simple way to improve your cat’s health. It is significant to the health of your cat’s immune system, nervous system, and digestive tract. It’s crucial for healthy cognitive function and helps your cat’s digestion. When you give your cat a B12 shot, you can see an improvement in their behavior within days. As a result, they are healthier and less stressed!

Vitamin B12 is given to cats for a variety of reasons. Water-soluble vitamin B12, also called cobalamin, is excreted in urine by cats when it becomes too much. Cats who need Vitamin B12 injections generally have poor health or other diseases. 

Let us see under what circumstances your cat may need a shot!

The importance of Vitamin B12

Among its many functions, B12 plays a vital role in maintaining the adrenal function, maintaining a healthy nervous system, producing DNA and RNA, and producing neurotransmitters. Myelination protects and covers nerve endings, affecting the development and maintenance of red blood cells. Anemia cannot be prevented without it, and it is also essential to proper digestion, absorption, and fat and carbohydrate metabolism.

In addition to nausea, vomiting, loss of appetite, constipation, gas, weight loss, fatigue, lethargy, abdominal pain, and diarrhea caused by B12 deficiency, vitamin B12 deficiency can also cause a severe neurological condition called malabsorption syndrome. It is necessary for the stomach, pancreas, and small intestine to function normally for B12 to be absorbed. IBD and other gastroenterological disorders exhibit these same symptoms in cats. Deficient B12 can also cause neurological disorders and severe and sometimes irreversible nerve damage by inhibiting and decreasing the body’s ability to produce blood, increasing blood cell destruction, and causing neurological disorders. Deficits may not be evident for a long time because a healthy liver store many years’ worth of B12.

Cases Where Vitamin B12 Shots May Be Needed

Cats with Diabetes

Peripheral neuropathy is one of the most common complications of diabetes. You will notice that your cat becomes shaky on its back legs if inflicted with this illness. A pet with diabetic peripheral neuropathy eventually regains full use of its rear legs in a few months, provided that vitamin B12 shots are administered. Ask your veterinarian about the correct dosage. And how to inject vitamin B12 into your diabetic cat if you are already skilled.

Cats with Illnesses of the Digestive System

Your veterinarian may suggest vitamin B12 shots to treat cat irritable bowel disease. Some cats and dogs with gastrointestinal diseases have a significant cobalamin deficiency at the tissue level. Serum cobalamin levels should be measured in cats with a history of chronic gastrointestinal disease.

Cats with Kidney Disease

Vitamin B12 injections are a good option for cats with kidney disease or renal failure. A failing kidney increases urine volume, causing water-soluble vitamins in the B category to leave the body more quickly. A cat receives additional B vitamins by supplementing with vitamin B12 injections, which may stimulate appetite.

Cats with Other Poor Conditions

Vitamin B12 shots help stray, stressed, elderly,r obese, and cats that consume poor diets. The animal is given better-quality food under veterinary supervision as part of such treatment. It is possible for a cat that is lethargic, depressed, and not eating well to be revived by vitamin B12 shots. In cases of anemia caused by poor care or flea infestations, veterinarians recommend B12 shots for cats.

Always consult your veterinarian before changing your pet’s diet, medication, or activity routine. A veterinarian’s advice is still more robust and more preferred.

What is Cyanocobalamin?

The use of cyanocobalamin (vitamin B12 or cobalamin) is common practice in treating metabolic or genetic deficiencies of vitamin B12. It can sometimes be used ‘off label’ or ‘extra label’ in treating vitamin deficiencies in cats and dogs. It is common for veterinary medicine to prescribe drugs for off-label use. You should follow your veterinarian’s instructions and caution since their instructions may differ significantly from those on the label.

Vitamin B12-Rich Foods

You may need to consider changing your cat’s diet if they show signs of vitamin B12 deficiency even though they are eating normally. Adding more meat to your dog’s diet, such as boiled chicken, fish, or cooked liver (unseasoned), is a good idea.


Before positive results are seen with cyanocobalamin treatment, it may take several weeks.


The oral tablet form of cyanocobalamin or the injectable solution form of this vitamin is given by mouth. Occasionally, your veterinarian may demonstrate how to inject this medication properly.

Missed Doses

Dosing should be started immediately. If forgetting to administer your pet’s monthly dose on the 1st and remember on the 18th, administer the dose on the 18th and initiate a new monthly schedule. You will administer your pet’s next dose on the 18th. Never administer two doses at once to your pet.

Side Effects

Despite its long-acting nature, this supplement appears to be well tolerated by animals. There may be some stinging during the injection, but it usually subsides within a few minutes. There is a possibility that this medication will have a few days’ worth of effects.

Risk Factors

Using injectables and oral medications in pets is not associated with known risks. Young animals and nursing mothers are likely to be able to use it safely.



Your feline babies will immensely benefit from vitamin B12 shots, but before changing your pet’s diet, medication, or physical activity routine, make sure you speak to your veterinarian regularly.

Frequently Asked Questions

What is the recommended frequency of B12 shots for cats?

For as long as you live, people with vitamin B12 deficiency will usually require hydroxocobalamin injections every 2 to 3 months if they inject vitamin B12 into their diets.

Is B12 helpful for cats’ appetites?

When administered to cats, vitamin B12 helps them feel more lively and stimulates their appetite. Unlike its synthetic counterpart, cyanocobalamin, this B12 supplement is much more effective when given to cats because it is readily absorbed.

Is it possible for your cat to feel better by taking vitamin shots?

When your cat feels blah, the vet will often give him a quick Vitamin B12 shot to make him feel better. You can give your cats B12 for cats once a week at home to stimulate their appetite if they suffer from chronic diseases.

What causes cats to be deficient in B12?

Cats and dogs with chronic, severe small intestinal disease are most likely to suffer from cobalamin deficiency. There is also a possibility that exocrine pancreatic insufficiency (EPI) may be a cause of hereditary cobalamin deficiency in certain dog breeds (including Border Collies).